Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 May-Aug;12(2):182-184.
doi: 10.4103/apc.APC_77_18.

Successful management of a neonate with antenatally detected mature intrapericardial teratoma

Affiliations

Successful management of a neonate with antenatally detected mature intrapericardial teratoma

Annie Arvind et al. Ann Pediatr Cardiol. 2019 May-Aug.

Abstract

Intrapericardial teratoma is a germ-cell tumor that typically arises from the base of the heart and usually diagnosed in the fetal or neonatal period. Although benign, these tumors can be massive in size causing direct compression of the heart. Life-threatening complications such as fetal hydrops, cardiac failure, superior vena cava syndrome, and cardiac tamponade caused by these teratomas have been reported. Early surgical excision is curative. We present the images of a mature intrapericardial teratoma diagnosed in an asymptomatic neonate. The neonate was managed successfully by elective surgical excision.

Keywords: Germ-cell tumor; intrapericardial teratoma; surgical excision; two-dimensional echocardiography.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Echocardiographic subcostal four-chamber view (a) demonstrating a heterogeneous mass (arrow) with multiple hypolucent cystic areas compressing the right atrium, with mild pericardial effusion. Unobstructed superior vena cava flow on color Doppler (b). The tumor mass measures 5 cm × 3.5 cm on subcostal coronal view (c). LV: Left ventricle, RV: Right ventricle, LA: Left atrium
Figure 2
Figure 2
(a and b) Computed tomography of the chest shows an intrapericardial mass (star) on the right side of the heart, adherent to the ascending aorta (arrow), and compressing the right atrium
Figure 3
Figure 3
(a) Gross pathological specimen of the bosselated intrapericardial mass measuring about 6 cm in greatest diameter, with a smooth external surface. Cystic areas are seen. (b) The intraoperative image of the tumor adherent to the ascending aorta
Figure 4
Figure 4
Photomicrograph showing (a) mature glandular tissue (yellow arrow) and (b) mature neural tissue in rosettes (blue arrow) (H and E, ×10 and × 40, respectively)

References

    1. Agozzino L, Vosa C, Arciprete P, de Leva F, Cotrufo M. Intrapericardial teratoma in the newborn. Int J Cardiol. 1984;5:21–8. - PubMed
    1. Manoly I, Viola N, Fowler D, Roman K, Haw M. Intrapericardial teratoma in neonates: A surgical emergency. World J Pediatr Congenit Heart Surg. 2011;2:321–3. - PubMed
    1. Gonzalez-Crussi F. Atlas of Tumor Pathology. Washington: Armed Forces Institute of Pathology; 1982. Extragonadal teratomas; pp. 1–44. 129. 2nd Ser. Fascicle 18.
    1. Sumner TE, Crowe JE, Klein A, McKone RC, Weaver RL. Intrapericardial teratoma in infancy. Pediatr Radiol. 1980;10:51–3. - PubMed
    1. Farooki ZQ, Arciniegas E, Hakimi M, Clapp S, Jackson W, Green EW, et al. Real-time echocardiographic features of intrapericardial teratoma. J Clin Ultrasound. 1982;10:125–8. - PubMed