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Review
. 2019 Jan-Jun;40(1):6-12.
doi: 10.4103/ijstd.IJSTD_23_19.

Genital lichen sclerosus et atrophicus in females: An update

Yogesh Marfatia  1 , Ashma Surani  1 , Reema Baxi  1
Affiliations
Review

Genital lichen sclerosus et atrophicus in females: An update

Yogesh Marfatia et al. Indian J Sex Transm Dis AIDS. 2019 Jan-Jun.

Abstract

Lichen sclerosus et atrophicus is an acquired chronic inflammatory dermatosis commonly affecting the vulvar and perianal regions. It is associated with an increased risk of vulvar cancer even though it is not a premalignant condition itself. The true precursor of cancer associated with lichen sclerosus (LS) is vulvar intraepithelial neoplasia (VIN), differentiated type. The diagnosis is usually clinical, but in some cases, a biopsy can be performed, especially to exclude VIN or cancer. All females with anogenital LS can be offered clobetasol propionate 0.05% ointment on a regimen for 3 months (once a day for a month, followed by alternative days for a month, and then, twice weekly for a month), combined with a soap substitute and a barrier preparation.

Keywords: Clobetasol propionate 0.05% ointment; genital lichen sclerosus et atrophicus; pruritus; vulvar intraepithelial neoplasia malignancy.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
(a) 57 year old female with pruritic white atrophied patches involving labia majora and bilateral groinfolds. (b)- 10 year old girl with external genital mucosal atrophy leading toloss of labia minora ,burrying of clitoris and progressive stenosis of intoitus. (c) 12 year old girl with erosions on white artophied patches on vulva
Figure 2
Figure 2
Figure of eight appearance in 59 year old female diagnosed with LSa
See this image and copyright information in PMC

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