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. 2019 May 29;14(1):56.
doi: 10.1007/s11657-019-0607-0.

The impact of hip fracture on health-related quality of life and activities of daily living: the SPARE-HIP prospective cohort study

D Prieto-Alhambra  1   2   3 , D Moral-Cuesta  4 , A Palmer  5 , I Aguado-Maestro  6 , M F Bravo Bardaji  7 , F Brañas  8 , G Adrados Bueno  9 , J R Caeiro-Rey  10 , I Andrés Cano  11 , M Barres-Carsi  12 , L Gracia Delgado  13 , M Salomó-Domènech  14 , I Etxebarria-Foronda  15 , B Llado Ferrer  16 , S Mills  17 , L Ezquerra Herrando  18 , D Mifsut  19 , L D R Evangelista  20 , X Nogués  21 , I Perez-Coto  22 , J Martínez-Iñiguez Blasco  23 , C Martín-Hernández  24 , H Kessel  25 , J Teixidor Serra  26 , J Rodriguez Solis  27 , O Torregrosa Suau  28 , E Vaquero-Cervino  29 , C Pablos Hernández  30 , L Rodríguez Mañas  31 , A Herrera  32 , A Díez-Perez  33
Affiliations

The impact of hip fracture on health-related quality of life and activities of daily living: the SPARE-HIP prospective cohort study

D Prieto-Alhambra et al. Arch Osteoporos. .

Abstract

Purpose: The medical morbidity and mortality associated with neck of femur fractures is well-documented, whereas there is limited data for patient-reported outcomes. The aim of this study was to characterize the impact of neck of femur fractures on activities of daily living and patient-reported health-related quality of life.

Methods: Design and participants: Multicentric prospective cohort study. Consecutive sample patients with fragility hip fracture over 50 years old admitted in 48 hospitals in Spain.

Outcomes: daily living activity function (Barthel Index) and health-related quality of life (EQ-5D) pre-fracture, admission to hospital and at 1- and 4-month follow-up post-fracture.

Statistics: Barthel and EQ-5D over time are described as mean (SD) and median (interquartile range).

Results: A total of 997 patients were recruited at baseline with 4-month outcomes available for, and 856 patients (89.5%). Barthel Index fell from 78.77 (23.75) at baseline to 43.62 (19.86) on admission to hospital with the fracture. Scores partially recovered to 54.89 (25.40) and 64.09 (21.35) at 1- and 4-month post-fracture, respectively. EQ-5D fell from a median of 0.75 (0.47-0.91) to - 0.01 (- 0.03 to 0.51) on admission. Partial recovery was observed again to (0.51 (- 0.06 to 0.67)) and (0.60 (0.10 to 0.80)) at 1- and 4-month post-fracture, respectively.

Conclusions: Hip fracture results in a large decline in the ability to perform activities of daily living and patient-reported health-related quality of life with only partial recovery amongst survivors 4-month post-fracture.

Keywords: Fragility hip fracture; Osteoporosis; Quality of life; Registries.

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Conflict of interest statement

ADP is advisor or speaker for Amgen/UCB, Roche, Gilead, EchoLight and Lilly. Institutional grant EchoLight and Kiowa-Kirin and Shareholder Active Life Sci. DPA’s research group has received unrestricted research grants from Servier, Amgen and UCB; and speaker and consultancy fees from Amgen and UCB. All other authors report no conflict of interests.

Figures

Fig. 1
Fig. 1
Histogram of EQ-5D-3L utility indices at baseline (pre-fx), at admission for a femur fracture (fx date), and at 1 and 4 months of follow-up
See this image and copyright information in PMC

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