Lenalidomide in the management of eosinophilic dermatosis of hematological malignancy

Abstract

Eosinophilic dermatosis of hematological malignancy is a paraneoplastic skin eruption associated with chronic lymphocytic leukemia and other B-cell malignancies. It clinically resembles an insect bite reaction and it can precede the symptoms of the hematological malignancy or be related to a more aggressive course. Different treatments have been proposed, but partial response and recurrence are frequent. Herein, we describe a case of eosinophilic dermatosis associated with mantle cell lymphoma with remission after lenalidomide therapy.

Keywords: eosinophilic dermatosis of hematological malignancy; eosinophilic reactive dermatoses; hematological malignancies; lenalidomide; paraneoplastic disorders.