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. 2019 Sep:137:104184.
doi: 10.1016/j.fitote.2019.104184. Epub 2019 May 28.

New phthalide derivatives from the Biscogniauxia sp. and their activities

Yan-Ying Liu  1 , Huan Zhao  2 , Jun Xie  1 , Jian Zou  1 , Dan Hu  1 , Liang-Dong Guo  3 , Guo-Dong Chen  4 , Xin-Sheng Yao  1 , Hao Gao  5
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New phthalide derivatives from the Biscogniauxia sp. and their activities

Yan-Ying Liu et al. Fitoterapia. 2019 Sep.

Abstract

Five new phthalide derivatives, biscogniphthalides A-D (1, 2, 3a/3b, and 4), were isolated from Biscogniauxia sp. (No. 69-8-7-1), along with one related known phthalide (5). Their structures were determined by comprehensive spectroscopic analyses, chemical derivatization, and quantum chemical ECD calculations. In addition, the anti-acetyl cholinesterase, antimicrobial, and anti-α-glucosidase activities of 1-5 were evaluated.

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