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Comment
. 2019 Jul;9(7):819-820.
doi: 10.1158/2159-8290.CD-NB2019-062. Epub 2019 May 30.

Scientists See Human Cancer in Zebrafish

No authors listed
Comment

Scientists See Human Cancer in Zebrafish

No authors listed. Cancer Discov. 2019 Jul.

Abstract

Researchers have developed an immune-deficient adult zebrafish model that engrafts a variety of human cancers, allowing them to visualize tumor growth at single-cell resolution and track responses to drug therapy. Using the model, they identified a possible treatment for rhabdomyosarcoma.

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Comment on

  • Visualizing Engrafted Human Cancer and Therapy Responses in Immunodeficient Zebrafish.
    Yan C, Brunson DC, Tang Q, Do D, Iftimia NA, Moore JC, Hayes MN, Welker AM, Garcia EG, Dubash TD, Hong X, Drapkin BJ, Myers DT, Phat S, Volorio A, Marvin DL, Ligorio M, Dershowitz L, McCarthy KM, Karabacak MN, Fletcher JA, Sgroi DC, Iafrate JA, Maheswaran S, Dyson NJ, Haber DA, Rawls JF, Langenau DM. Yan C, et al. Cell. 2019 Jun 13;177(7):1903-1914.e14. doi: 10.1016/j.cell.2019.04.004. Epub 2019 Apr 25. Cell. 2019. PMID: 31031007 Free PMC article.

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