Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Mar 19;6(3):109-113.
doi: 10.1007/s13691-017-0285-y. eCollection 2017 Jul.

A case of low-grade appendiceal mucinous neoplasm with invagination resected laparoscopically

Toshiaki Yoshimoto  1 , Masaaki Nishi  1 , Kozo Yoshikawa  1 , Jun Higashijima  1 , Takuya Tokunaga  1 , Toshihiro Nakao  1 , Hideya Kashihara  1 , Chie Takasu  1 , Daichi Ishikawa  1 , Yoshimi Bando  2 , Mitsuo Shimada  1
Affiliations
Case Reports

A case of low-grade appendiceal mucinous neoplasm with invagination resected laparoscopically

Toshiaki Yoshimoto et al. Int Cancer Conf J. .

Abstract

Low-grade appendiceal mucinous neoplasm (LAMN) is rare disease, and the absence of characteristic clinical symptoms makes preoperative diagnosis difficult. The strategy of treatment for LAMN has not been established. Surgical approach and lymph node (LN) dissection are still controversial. We herein present a case of LAMN with difficulties in making the preoperative diagnosis, which exhibited invagination and was treated by laparoscopy-assisted ileocecal resection with LN dissection. When cystic mass is detected in the bowel, LAMN or mucinous adenocarcinoma should be considered as a different diagnosis. And the laparoscopy-assisted ileocecal resection is a feasible operation for LAMN with careful procedure.

Keywords: Appendiceal mucocele; Appendix; Low-grade appendiceal mucinous neoplasm.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.Informed consent was obtained from all individual participants included in the study.

Figures

Fig. 1
Fig. 1
Abdominal CT scan (a and b) showed smooth cystic bulge with calcification at the left side of the lesion (arrow). It showed a concentric circles structure (b)
Fig. 2
Fig. 2
Colonoscopy revealed a submucosal tumor in the transverse colon, and it was moved easily to cecum (a). CT colonography showed smooth hemispheric defect of the cecum (b)
Fig. 3
Fig. 3
Macroscopic view of the resected specimen showed the sub-mucosal tumor originated from appendix and the appendiceal orifice (arrows). The tumor was filled with jelly-like mucus (a and b). Histopathologic image demonstrating the papillary growing glandular epithelium covered by a single layer of columnar mucinous cells, and elongate swelling nuclei at the base (c)
See this image and copyright information in PMC

References

    1. Farah-Klibi F, Kourda-Boujemaa J, Bouaskar I, et al. Cystadenocarcinoma of the appendix: an incidental perioperatory finding in a patient with adenocarcinoma of the ascending and sigmoid colon: case report and review of literature. Pathologica. 2009;101(6):255. - PubMed
    1. Kalogiannidis I, Mavrona A, Grammenou S, et al. Endometrial adenocarcinoma and mucocele of the appendix: an unusual coexistence. Case Rep Obstet Gynecol. 2013 - PMC - PubMed
    1. Murata Y, Goshima H, Kato H, et al. Two cases of mucocele of the appendix with acute abdomen. Mie-igaku. 2006;49(3):63–66.
    1. Nakatani K, Tokuhara K, Sakaguchi T, et al. Low-grade mucinous neoplasia in a cecal diverticulum: a case report. Int J Surg Case Rep. 2015;15:66–69. doi: 10.1016/j.ijscr.2015.08.030. - DOI - PMC - PubMed
    1. Spyropoulos C, Rentis A, Alexaki E, et al. Appendiceal mucocele and pseudomyxoma peritonei; the clinical boundaries of a subtle disease. Am J Case Rep. 2014;15:355. doi: 10.12659/AJCR.890837. - DOI - PMC - PubMed

Publication types

LinkOut - more resources