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Comment
. 2019 Jun 11;58(23):2653-2654.
doi: 10.1021/acs.biochem.9b00102. Epub 2019 May 31.

IID in 3D: Improved Resolution of Transcription Factor Structure by Cryo-Electron Microscopy

Jordan T Feigerle  1 , Roger D Kornberg  1
Affiliations
Comment

IID in 3D: Improved Resolution of Transcription Factor Structure by Cryo-Electron Microscopy

Jordan T Feigerle et al. Biochemistry. .
No abstract available

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Figures

Figure 1:
Figure 1:
Apo- and DNA-bound TFIID Structures. A) TFIID structure demonstrating the resolution revealed by focused refinement. Low resolution complete 3D class average in light grey, BC core masked region shown in light blue, Lobe A masked region in light yellow. B) Modeled structure of all 14 TFIID subunits. C) Structure of TFIID-TFIIA-promoter DNA in the engaged state. BC Core in light blue. Lobe A in light yellow, TBP in red, TFIIA in orange, DNA in aquamarine. D) Low resolution structure of TFIID displaying mobility of Lobe A. TFIID BC core in cyan, Lobe A in canonical position in yellow and Lobe A in extended position in green. All images derived with modification from Patel et al. 2018.
See this image and copyright information in PMC

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References

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