Antibiotic Lethality Is Impacted by Nutrient Availabilities: New Insights from Machine Learning
- PMID: 31150617
- DOI: 10.1016/j.cell.2019.05.015
Antibiotic Lethality Is Impacted by Nutrient Availabilities: New Insights from Machine Learning
Abstract
In this issue of Cell, Yang, Wright et al. describe a machine learning approach that that can provide mechanistic insight from chemical screens. They use this approach to uncover how the nutritional availability for Escherichia coli impacts lethality toward three widely used antibiotics.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.Cell. 2019 May 30;177(6):1649-1661.e9. doi: 10.1016/j.cell.2019.04.016. Epub 2019 May 9. Cell. 2019. PMID: 31080069 Free PMC article.
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