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Review
. 2019 Oct;48(10):1131-1137.
doi: 10.1016/j.lpm.2019.04.005. Epub 2019 May 29.

Therapeutic innovations in breast cancer

Fanny Le Du  1 , Christophe Perrin  1 , Angélique Brunot  1 , Laurence Crouzet  1 , Thibault De La Motte Rouge  1 , Claudia Lefeuvre-Plesse  1 , Véronique Dieras  2
Affiliations
Review

Therapeutic innovations in breast cancer

Fanny Le Du et al. Presse Med. 2019 Oct.

Abstract

Managing endocrine resistance and resistance to endocrine therapy for ER+ HER2- breast cancer with the CDK 4/6 inhibitors in the metastatic setting. New antibodies drug conjugates for HER2+ and TNBC. Targeting DNA damage and synthetic lethality strategies with PARP inhibitors for breast cancer patients harboring BRCA mutation. Immunotherapies in 1st line metastatic setting of TNBC.

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