Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 May 30;12(5):e229354.
doi: 10.1136/bcr-2019-229354.

Junctional bradycardia caused by ciguatera intoxication

Affiliations
Case Reports

Junctional bradycardia caused by ciguatera intoxication

Rajendra Raman et al. BMJ Case Rep. .

Abstract

Ciguatera is a common but underreported tropical disease caused by the consumption of coral reef fish contaminated by ciguatoxins. Gastrointestinal and neurological symptoms predominate, but may be accompanied by cardiovascular features such as hypotension and sinus bradycardia. Here, we report an unusual case of junctional bradycardia caused by ciguatera in the Caribbean; to our knowledge, the first such report from the region. An increase in global sea temperatures is predicted to lead to the spread of ciguatera beyond traditional endemic areas, and the globalisation of trade in coral reef fish has resulted in sporadic cases occurring in developed countries far away from endemic areas. This case serves as a reminder to consider environmental intoxications such as ciguatera within the differential diagnosis of bradycardias.

Keywords: arrhythmias; poisoning.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
ECG at presentation showing junctional bradycardia of 45/min with sinus node arrest and retrograde atrial depolarisation.
Figure 2
Figure 2
ECG at follow-up, showing normal sinus rhythm at 60/min.

Similar articles

Cited by

References

    1. Heimann K, Sparrow L. Ciguatera: tropical reef fish poisoning Kim S-K, Handbook of marine microalgae. London: Elsevier, 2015:547–58.
    1. Friedman MA, Fernandez M, Backer LC, et al. . An updated review of ciguatera fish poisoning: clinical, epidemiological, environmental, and public health management. Mar Drugs 2017;15:72 10.3390/md15030072 - DOI - PMC - PubMed
    1. Pottier I, Vernoux JP, Lewis RJ. Ciguatera fish poisoning in the Caribbean islands and Western Atlantic. Rev Environ Contam Toxicol 2001;168:99–141. - PubMed
    1. Geller RJ, Benowitz NL. Orthostatic hypotension in ciguatera fish poisoning. Arch Intern Med 1992;152:2131–3. 10.1001/archinte.1992.00400220135023 - DOI - PubMed
    1. Schnorf H, Taurarii M, Cundy T. Ciguatera fish poisoning: a double-blind randomized trial of mannitol therapy. Neurology 2002;58:873–80. 10.1212/WNL.58.6.873 - DOI - PubMed

Publication types