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Comment
. 2019 Jul;27(7):565-566.
doi: 10.1016/j.tim.2019.05.004. Epub 2019 May 30.

Ebola Virus Replication Stands Out

Wenjie Wang  1 , Chao Wu  1 , Gaya K Amarasinghe  1 , Daisy W Leung  2
Affiliations
Comment

Ebola Virus Replication Stands Out

Wenjie Wang et al. Trends Microbiol. 2019 Jul.

Abstract

A recent study by Deflubé et al. (Proc. Natl. Acad. Sci. U. S. A. 2019;116:8535-8543) reported that Ebola virus genomes have variable 3' terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.

Keywords: Ebola virus; innate immune evasion; replication initiation.

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References

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