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Comparative Study
. 1987 Oct 9;51(1):113-9.
doi: 10.1016/0092-8674(87)90015-8.

A new class of yeast transcriptional activators

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Comparative Study

A new class of yeast transcriptional activators

J Ma et al. Cell. .

Abstract

We describe yeast transcriptional activators encoded by E. coli genomic DNA fragments fused to the coding sequence of the DNA-binding portion of GAL4. All of the new activating sequences that we have analyzed, like those of GAL4 and GCN4, are acidic; most of these sequences show no obvious sequence homology when compared with the identified activating regions of GAL4 and GCN4 or among themselves. We also describe a fusion protein that contains no yeast protein sequence but activates transcription in yeast.

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Comment in

  • Two "what if" experiments.
    Ptashne M. Ptashne M. Cell. 2004 Jan 23;116(2 Suppl):S71-2, 2 p following S76. doi: 10.1016/s0092-8674(03)01076-6. Cell. 2004. PMID: 15055587 No abstract available.
  • Actively seeking activating sequences.
    Ma J. Ma J. Cell. 2004 Jan 23;116(2 Suppl):S75-6, 2 p following S76. doi: 10.1016/s0092-8674(03)01033-x. Cell. 2004. PMID: 15055589 No abstract available.

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