Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Mar 19;11(3):e4277.
doi: 10.7759/cureus.4277.

Does Bupropion Impact More than Mood? A Case Report and Review of the Literature

Affiliations
Case Reports

Does Bupropion Impact More than Mood? A Case Report and Review of the Literature

Waqas Yasin et al. Cureus. .

Abstract

Sexual side effects are often an unintended consequence of antidepressant treatment. Given antidepressants of different classes are frequently paired together in order to improve therapeutic response, understanding their interplay in regards to sexual functioning is important. Bupropion is an atypical antidepressant which is often used as a Selective Serotonin Reuptake Inhibitors adjunct in the treatment of depression, as well as in the amelioration of decreased libido. The following case highlights the importance of understanding antidepressant medications and their combined potential effect on sexual function to prevent unnecessary complications in cases involving the history of paraphilic disorders and hypersexuality.

Keywords: bupropion; hypersexuality disorder; selective serotonin reuptake inhibitors (ssri).

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

References

    1. The pharmacologic basis for therapeutic interest in bupropion. Soroko FE, Maxwell RA. https://europepmc.org/abstract/med/6406467. J Clin Psychiatry. 1983;44:67–73. - PubMed
    1. A review of the neuropharmacology of bupropion, a dual norepinephrine and dopamine reuptake inhibitor. Stahl SM, Pradko JF, Haight BR, Modell JG, Rockett CB, Learned-Coughlin S. Prim Care Companion J Clin Psychiatry. 2004;6:159–166. - PMC - PubMed
    1. A dissociation of the acute effects of bupropion on positive emotional processing and reward processing in healthy volunteers. Walsh AEL, Huneke NTM, Brown R, Browning M, Cowen P, Harmer CJ. Front Psychiatry. 2018;9:482. - PMC - PubMed
    1. Bupropion-sustained release as a treatment for SSRI-induced sexual side effects. Gitlin MJ, Suri R, Altshuler L, Zuckerbrow-Miller J, Fairbanks L. J Sex Marital Ther. 2002;28:131–138. - PubMed
    1. Effect of bupropion on sexual dysfunction induced by fluoxetine: a case report of hypersexuality. Chollet CA, Andreatini R. https://www.ncbi.nlm.nih.gov/pubmed/14658981. J Clin Psychiatry. 2003;64:1268–1269. - PubMed

Publication types

LinkOut - more resources