Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1978 Nov;30(6):653-9.

A new allele of human alpha1-antitrypsin: PiNhampton

P Arnaud, R M Galbraith, G M Galbraith, R C Allen, H H Fudenberg
Case Reports

A new allele of human alpha1-antitrypsin: PiNhampton

P Arnaud et al. Am J Hum Genet. 1978 Nov.

Abstract

A new allele of alpha1AT is described. By isoelectric focusing, the microheterogeneous pattern of the variant was similar to but more cathodal than that of Pi N. This allele has therefore been tentatively designated PiNhampton(Nham). Further examination revealed that the minor bands of Nham are indistinguishable from the major bands of Z by isoelectric focusing, and a careful family study was necessary to clearly define the proband's phenotype. Pi Nham was found in association with M1, S, and Z, but to date its possession is not apparently related to clinical disorders or reduced serum levels of alpha1AT.

PubMed Disclaimer

References

    1. J Immunol Methods. 1977;16(3):221-31 - PubMed
    1. J Clin Invest. 1977 Dec;60(6):1442-4 - PubMed
    1. Clin Genet. 1977 Aug;12(2):77-9 - PubMed
    1. Hum Genet. 1977 Oct 14;38(3):325-32 - PubMed
    1. Hum Genet. 1977 Jul 26;37(3):303-13 - PubMed

Publication types

Substances

LinkOut - more resources