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Comment
. 2019 Aug;26(8):940-943.
doi: 10.1111/acem.13811. Epub 2019 Jul 18.

Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial

Abhishek G Sathe  1 , Holly Tillman  2 , Lisa D Coles  1 , Jordan J Elm  2 , Robert Silbergleit  3 , James Chamberlain  4 , Jaideep Kapur  5   6 , Hannah R Cock  7 , Nathan B Fountain  5 , Shlomo Shinnar  8 , Daniel H Lowenstein  9 , Robin A Conwit  10 , Thomas P Bleck  11 , James C Cloyd  1
Affiliations
Comment

Underdosing of Benzodiazepines in Patients With Status Epilepticus Enrolled in Established Status Epilepticus Treatment Trial

Abhishek G Sathe et al. Acad Emerg Med. 2019 Aug.
No abstract available

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Figures

Figure 1:
Figure 1:
Distribution of first dose of the first administered benzodiazepine (DZP, MDZ or LZP) as actual doses. Top panel: fixed dosing, bottom panel: weight-based dosing. A:DZP doses for those ≥ 66.7kg (IV) or ≥ 50 kg (rectal); B: MDZ doses for those > 40 kg; C: LZP doses for those ≥ 40 kg; D: DZP doses for those < 66.7 kg (IV) or < 50 kg (rectal); E: MDZ doses for those ≤ 40 kg; F: LZP doses for those < 40 kg . Categorized as met (blue) or did not meet (red) guidelines.
See this image and copyright information in PMC

Comment on

  • Guidelines for the evaluation and management of status epilepticus.
    Brophy GM, Bell R, Claassen J, Alldredge B, Bleck TP, Glauser T, Laroche SM, Riviello JJ Jr, Shutter L, Sperling MR, Treiman DM, Vespa PM; Neurocritical Care Society Status Epilepticus Guideline Writing Committee. Brophy GM, et al. Neurocrit Care. 2012 Aug;17(1):3-23. doi: 10.1007/s12028-012-9695-z. Neurocrit Care. 2012. PMID: 22528274

References

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Substances

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