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Comment
. 2019 Aug;9(8):OF6.
doi: 10.1158/2159-8290.CD-NB2019-065. Epub 2019 Jun 4.

Maintenance Olaparib New Standard in Pancreatic Cancer?

No authors listed
Comment

Maintenance Olaparib New Standard in Pancreatic Cancer?

No authors listed. Cancer Discov. 2019 Aug.

Abstract

In a phase III trial, olaparib maintenance therapy significantly extended progression-free survival and duration of response in patients with BRCA-mutated metastatic pancreatic cancer who responded to platinum-based chemotherapy, compared with a placebo. Based on the findings, which were presented at the 2019 American Society of Clinical Oncology Annual Meeting in Chicago, IL, maintenance olaparib is likely to become a new treatment option for these patients.

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  • Maintenance Olaparib for Germline BRCA-Mutated Metastatic Pancreatic Cancer.
    Golan T, Hammel P, Reni M, Van Cutsem E, Macarulla T, Hall MJ, Park JO, Hochhauser D, Arnold D, Oh DY, Reinacher-Schick A, Tortora G, Algül H, O'Reilly EM, McGuinness D, Cui KY, Schlienger K, Locker GY, Kindler HL. Golan T, et al. N Engl J Med. 2019 Jul 25;381(4):317-327. doi: 10.1056/NEJMoa1903387. Epub 2019 Jun 2. N Engl J Med. 2019. PMID: 31157963 Free PMC article. Clinical Trial.

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