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Meta-Analysis
. 2019 Aug 27;34(4):420-427.
doi: 10.21470/1678-9741-2018-0284.

Patency of Individual and Sequential Coronary Artery Bypass in Patients with Ischemic Heart Disease: A Meta-analysis

Zeshu Li  1   2 , Luqi Liu  2
Affiliations
Meta-Analysis

Patency of Individual and Sequential Coronary Artery Bypass in Patients with Ischemic Heart Disease: A Meta-analysis

Zeshu Li et al. Braz J Cardiovasc Surg. .

Erratum in

  • ERRATUM.
    [No authors listed] [No authors listed] Braz J Cardiovasc Surg. 2019 Dec 1;34(6):790. doi: 10.21470/1678-9741-2018-0284e. Braz J Cardiovasc Surg. 2019. PMID: 31793260 Free PMC article. No abstract available.

Abstract

Objective: To evaluate the patency of individual and sequential coronary artery bypass in patients with ischemic heart disease.

Methods: We searched PubMed, Cochrane Library, Excerpta Medica Database, and ClinicalTrials.gov databases for controlled trials. Endpoints included graft patency, anastomosis patency, occluded rates in left anterior descending (LAD) system and right coronary artery (RCA) system, in-hospital mortality, and follow-up mortality. Pooled risk ratios (RRs) and standardized mean difference (SMD) were used to assess the relative data.

Results: Nine cohorts, including 7100 patients and 1440 grafts under individual or sequential coronary artery bypass. There were no significant differences between individual and sequential coronary artery bypass in the graft patency (RR=0.96; 95% CI=0.91-1.02; P=0.16; I2=87%), anastomosis patency (RR=0.95; 95% CI=0.91-1.00; P=0.05; I2=70%), occluded rate in LAD system (RR=1.03; 95% CI=0.92-1.16; P=0.58; I2=37%), occluded rate in RCA system (RR=1.36; 95% CI=0.72-2.57; P=0.35; I2=95%), in-hospital mortality (RR=1.57; 95% CI=0.92-2.69; P=0.10; I2=0%), and follow-up mortality (RR=0.96; 95% CI=0.36-2.53; P=0.93; I2=0%).

Conclusion: No significant differences on clinical data were observed regarding anastomosis patency, occluded rate in LAD system, occluded rate in RCA system, in-hospital mortality, and follow-up mortality, indicating that the patency of individual and the patency of sequential coronary artery bypass are similar to each other.

Keywords: Coronary Artery Bypass; Coronary Artery Disease; Hospital Mortality; Meta-Analysis as Topic; Myocardial Ischemia.

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Conflict of interest statement

No conflict of interest.

Figures

Fig. 1
Fig. 1
Flowchart showing the progress of data selection.
Fig. 2
Fig. 2
Forest plot of graft patency. CI=confidence interval
Fig. 3
Fig. 3
Forest plot of anastomosis patency. CI=confidence interval
Fig. 4
Fig. 4
Forest plot of occluded rate in LAD system. CI=confidence interval; LAD=left anterior descending
Fig. 5
Fig. 5
Forest plot of occluded rate in RCA system. CI=confidence interval; RCA=right coronary artery
Fig. 6
Fig. 6
Forest plot of in-hospital mortality. CI=confidence interval
Fig. 7
Fig. 7
Forest plot of follow-up mortality. CI=confidence interval
Fig. 8
Fig. 8
Sensitivity analysis of excluding each individual study. Cl=control
See this image and copyright information in PMC

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