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. 2019 Aug 1;155(8):971-973.
doi: 10.1001/jamadermatol.2019.0478.

Distribution of Self-reported Hidradenitis Suppurativa Age at Onset

Haley B Naik  1 , Maia Paul  1 , Steven R Cohen  2 , Afsaneh Alavi  3   4 , Mayte Suàrez-Fariñas  5   6 , Michelle A Lowes  7
Affiliations

Distribution of Self-reported Hidradenitis Suppurativa Age at Onset

Haley B Naik et al. JAMA Dermatol. .

Abstract

This cohort study examines the median age at onset of hidradenitis suppurativa and compares age at onset across sex, race, and disease severity of individuals.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr Naik has performed consulting work for 23andMe and is a coinvestigator on a grant from AbbVie. Dr Alavi has performed consulting work for AbbVie, Janssen, LEO, Galderma, Novartis, and Valeant; is an investigator for AbbVie, Novartis, Regeneron, Pfizer, Boehringer Ingelheim, Glenmark, Merck Serono, Roche, Xoma, and Xenon; and has received an unrestricted educational grant from AbbVie. Dr Cohen has served as a principal investigator on 2 grants from AbbVie and is on the Scientific Advisory Board of Verrica Pharmaceuticals. Dr Suàrez-Fariñas has received grant funding from Pfizer, Novartis, and AllerGenis, and has consulted for DBV and NEA. Dr Lowes has participated in advisory boards for AbbVie and Janssen, and has consulted for Almirall, Incyte, BSN, and XBiotech. Drs Naik and Lowes are also board members for the Hidradenitis Suppurativa Foundation. No other disclosures are reported.

Figures

Figure.
Figure.. Age at Onset in Patients With Hidradenitis Suppurativa
A, Overall distribution of all age at onset values showing the bimodal distribution of age at hidradenitis suppurativa presentation. B, Parametric bootstrapping identified 2 components in the mixture of distributions of age at onset (in log10 scale) using sex as a covariate. The estimated distribution for the common onset group centered around the late teen years (blue dot), and a late onset group around the 40s. Bars represent the location and SD range (calculated in the log10) in the original age at onset scale.
See this image and copyright information in PMC

References

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