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Case Reports
. 2019 Jul 1;155(7):859-861.
doi: 10.1001/jamadermatol.2019.0814.

Cutaneous Granulomatous Disease With Presence of Rubella Virus in Lesions

Julie Dhossche  1 , Luke Johnson  2 , Kevin White  1 , Tracy Funk  1 , Sabra Leitenberger  1 , Ludmila Perelygina  3 , Alfons Krol  1
Affiliations
Case Reports

Cutaneous Granulomatous Disease With Presence of Rubella Virus in Lesions

Julie Dhossche et al. JAMA Dermatol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure 1.
Figure 1.. Clinical and Histopathologic Images of Patient 1
A, Right cheek with erythematous papules coalescing into plaques. B, Right cheek with the granulomatous plaque 1 year after first presentation. C, Lesional biopsy specimen showing sarcoidal granulomas (hematoxylin-eosin). D, Immunofluorescent immunohistochemical staining of rubella virus capsid (red) in CD206-positive (green) M2 macrophages; nuclei counterstained with DAPI (blue).
Figure 2.
Figure 2.. Clinical and Histopathologic Images of Patient 2
A. Scaly erythematous to violaceous papulonodules over the extremities at initial presentation. B, More confluent, scaly, and scarring erythematous to violaceous plaques over bilateral lower extremities 8 years later. C, Immunofluorescent immunohistochemical staining of rubella virus capsid (red) in CD206-positive (green) M2 macrophages; nuclei counterstained with DAPI (blue). D, M2 syncytia (Langhans cells) containing rubella virus capsid.
See this image and copyright information in PMC

References

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