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Editorial
. 2019 Oct 1;200(7):795-796.
doi: 10.1164/rccm.201905-0953ED.

Advancing Understanding of Mechanisms of Severe Asthma and Drug Effects Using Transcriptomics

Ratko Djukanović  1   2
Affiliations
Editorial

Advancing Understanding of Mechanisms of Severe Asthma and Drug Effects Using Transcriptomics

Ratko Djukanović. Am J Respir Crit Care Med. .
No abstract available

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References

    1. Weathington N, O’Brien ME, Radder J, Whisenant TC, Bleecker ER, Busse WW, et al. BAL cell gene expression in severe asthma reveals mechanisms of severe disease and influences of medications Am J Respir Crit Care Med 2019200837–856 - PMC - PubMed
    1. Rossios C, Pavlidis S, Hoda U, Kuo CH, Wiegman C, Russell K, et al. Unbiased Biomarkers for the Prediction of Respiratory Diseases Outcomes (U-BIOPRED) Consortia Project Team. Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma. J Allergy Clin Immunol. 2018;141:560–570. - PubMed
    1. Kuo CS, Pavlidis S, Loza M, Baribaud F, Rowe A, Pandis I, et al. U-BIOPRED Study Group. T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED. Eur Respir J. 2017;49:1602135. - PubMed
    1. Modena BD, Bleecker ER, Busse WW, Erzurum SC, Gaston BM, Jarjour NN, et al. Gene expression correlated with severe asthma characteristics reveals heterogeneous mechanisms of severe disease. Am J Respir Crit Care Med. 2017;195:1449–1463. - PMC - PubMed
    1. Modena BD, Tedrow JR, Milosevic J, Bleecker ER, Meyers DA, Wu W, et al. Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. Am J Respir Crit Care Med. 2014;190:1363–1372. - PMC - PubMed