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Comparative Study
. 1986 Dec;67(4):289-94.
doi: 10.1016/0041-3879(86)90018-8.

Inhibition of virulent Mycobacterium tuberculosis by murine peritoneal macrophages and human alveolar lavage cells: the effects of lymphokines and recombinant gamma interferon

J Steele  1 , K C Flint, A L Pozniak, B Hudspith, M M Johnson, G A Rook
Affiliations
Comparative Study

Inhibition of virulent Mycobacterium tuberculosis by murine peritoneal macrophages and human alveolar lavage cells: the effects of lymphokines and recombinant gamma interferon

J Steele et al. Tubercle. 1986 Dec.

Abstract

Both murine peritoneal macrophages and human alveolar lavage cells inhibited growth of M. tuberculosis in a medium containing 10% foetal calf serum. However, whereas addition of recombinant gamma interferon or crude lymphokine reproducibly activated further strong anti-mycobacterial mechanisms in the murine cells, these stimuli had weak and variable effects on human alveolar cells.

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