Reply to "Is the Guytonian framework justified in explaining heart lung interactions?" and "Venous return, mean systemic pressure and getting the right answer for the wrong reason"

Affiliations

¹ Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
² Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital Östra, Gothenburg, Sweden.

Comment

David Berger et al. Ann Transl Med. 2019 Apr.

. 2019 Apr;7(8):186.

doi: 10.21037/atm.2019.04.50.

¹ Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
² Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital Östra, Gothenburg, Sweden.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Is the Guytonian framework justified in explaining heart-lung interactions?
Dalmau R. Dalmau R. Ann Transl Med. 2019 Apr;7(8):184. doi: 10.21037/atm.2019.03.41. Ann Transl Med. 2019. PMID: 31168465 Free PMC article. No abstract available.
Venous return, mean systemic pressure and getting the right answer for the wrong reason.
Brengelmann GL. Brengelmann GL. Ann Transl Med. 2019 Apr;7(8):185. doi: 10.21037/atm.2019.03.64. Ann Transl Med. 2019. PMID: 31168466 Free PMC article. No abstract available.

1. Berger D, Takala J. Determinants of systemic venous return and the impact of positive pressure ventilation. Ann Transl Med 2018;6:350. 10.21037/atm.2018.05.27 - DOI - PMC - PubMed
1. Lansdorp B, Hofhuizen C, van Lavieren M, et al. Mechanical ventilation-induced intrathoracic pressure distribution and heart-lung interactions*. Crit Care Med 2014;42:1983-90. 10.1097/CCM.0000000000000345 - DOI - PubMed
1. Berger D, Moller PW, Weber A, et al. Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. Am J Physiol Heart Circ Physiol 2016;311:H794-806. 10.1152/ajpheart.00931.2015 - DOI - PubMed
1. Fessler HE, Brower RG, Shapiro EP, et al. Effects of positive end-expiratory pressure and body position on pressure in the thoracic great veins. Am Rev Respir Dis 1993;148:1657-64. 10.1164/ajrccm/148.6_Pt_1.1657 - DOI - PubMed
1. Moller PW, Hana A, Heinisch PP, et al. The Effects of Vasoconstriction And Volume Expansion on Veno-Arterial ECMO Flow. Shock 2019;51:650-8. - PubMed