Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Aug;53(8):1902-6.
doi: 10.1128/aem.53.8.1902-1906.1987.

Carbon monoxide-dependent chemolithotrophic growth of Clostridium thermoautotrophicum

M D Savage  1 , Z G Wu, S L Daniel, L L Lundie Jr, H L Drake
Affiliations

Carbon monoxide-dependent chemolithotrophic growth of Clostridium thermoautotrophicum

M D Savage et al. Appl Environ Microbiol. 1987 Aug.

Abstract

The acetogen Clostridium thermoautotrophicum was cultivated under CO-dependent chemolithotrophic conditions. CO-dependent growth profiles and energetics indicated that supplemental CO2 was fundamental to efficient growth at the expense of CO. Overall product stoichiometry approximated 6.5CO----CH3CO2H + 3.5CO2 + 0.6 cell C + 0.5 unrecovered C. Initial CO/CO2 ratios of 2 to 4 yielded optimal doubling times and cell yields. Maximal YCO values approximated 2.5 g of cell dry weight per mol of CO consumed; YH2 was considerably lower than YCO. Cross-transfer growth experiments and protein profiles indicated differential expression of genes between CO and methanol cultures.

PubMed Disclaimer

References

    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. J Bacteriol. 1983 Mar;153(3):1415-23 - PubMed
    1. Proc Natl Acad Sci U S A. 1976 Sep;73(9):3298-302 - PubMed
    1. Appl Environ Microbiol. 1984 May;47(5):961-4 - PubMed
    1. J Biol Chem. 1980 Aug 10;255(15):7174-80 - PubMed

Publication types

MeSH terms

LinkOut - more resources