Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Jul 1;218(7):2433-2434.
doi: 10.1083/jcb.201905105. Epub 2019 Jun 6.

Reply to "Phosphorylation of G3BP1-S149 does not influence stress granule assembly"

Hélène Tourrière  1 , Jamal Tazi  2
Affiliations
Comment

Reply to "Phosphorylation of G3BP1-S149 does not influence stress granule assembly"

Hélène Tourrière et al. J Cell Biol. .

Abstract

In this issue, Panas et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201801214) challenge the data published in the Tourrière et al. (2013. J. Cell Biol. https://doi.org/10.1083/jcb.200212128) paper on the role of G3BP phosphorylation in stress granule (SG) assembly. This reply addresses that letter and suggests that more work is needed to understand the role of this modification in SG formation.

PubMed Disclaimer

Comment on

References

    1. Jedrusik-Bode M., Studencka M., Smolka C., Baumann T., Schmidt H., Kampf J., Paap F., Martin S., Tazi J., Müller K.M., et al. . 2013. The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals. J. Cell Sci. 126:5166–5177. 10.1242/jcs.130708 - DOI - PubMed
    1. Kwon S., Zhang Y., and Matthias P.. 2007. The deacetylase HDAC6 is a novel critical component of stress granules involved in the stress response. Genes Dev. 21:3381–3394. 10.1101/gad.461107 - DOI - PMC - PubMed
    1. Panas M.D., Kedersha N., Schulte T., Branca R.M., Ivanov P., and Anderson P.. 2019. Phosphorylation of G3BP-S149 does not influence stress granule assembly. J. Cell Biol. 10.1083/jcb.201801214 - DOI - PMC - PubMed
    1. Tourrière H., Chebli K., Zekri L., Courselaud B., Blanchard J.M., Bertrand E., and Tazi J.. 2003. The RasGAP-associated endoribonuclease G3BP assembles stress granules. J. Cell Biol. 160:823–831. 10.1083/jcb.200212128 - DOI - PMC - PubMed