Cancer screening and prevention in BRCA mutation carriers: a missed opportunity?
- PMID: 31171836
- PMCID: PMC6738056
- DOI: 10.1038/s41416-019-0484-8
Cancer screening and prevention in BRCA mutation carriers: a missed opportunity?
Abstract
While the elevated lifetime risk of breast and ovarian cancer is well recognised for patients with a BRCA mutation, the implementation of effective risk reduction strategies has been fraught with challenges. This report from an international database and published in the British Journal of Cancer reveals suboptimal rates of utilisation of surveillance/preventative measures globally.
Conflict of interest statement
S.C. is a member of the Editorial Board of the
Comment on
-
International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation.Br J Cancer. 2019 Jul;121(1):15-21. doi: 10.1038/s41416-019-0446-1. Epub 2019 Apr 11. Br J Cancer. 2019. PMID: 30971774 Free PMC article.
References
-
- Paluch-Shimon S, Cardoso F, Sessa C, Balmana J, Cardoso MJ, Gilbert F, et al. Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening. Ann. Oncol. 2016;27(suppl 5):v103–v110. doi: 10.1093/annonc/mdw327. - DOI - PubMed
-
- Den Heijer M, van Asperen CJ, Harris H, Nippert I, Schmidtke J, Bouhnik AD, et al. International variation in physicians’ attitudes towards prophylactic mastectomy-comparison between France, Germany, the Netherlands and the United Kingdom. Eur. J. Cancer. 2013;49:2798–2805. doi: 10.1016/j.ejca.2013.04.025. - DOI - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
