Temperature-dependent expression of the chromosomal beta-lactamase gene in a strain of Pseudomonas aeruginosa
- PMID: 3118037
- DOI: 10.1099/00222615-24-3-263
Temperature-dependent expression of the chromosomal beta-lactamase gene in a strain of Pseudomonas aeruginosa
Abstract
A strain of Pseudomonas aeruginosa (3-Post) was resistant to cefsulodin and ceftazidime at 37 degrees C but sensitive at 20 degrees C. Resistance was mediated by chromosomally-encoded beta lactamase which was synthesised at a high level during growth above 30 degrees C but at a low, inducible level during growth below 27 degrees C.
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