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Review
. 2019 Jun 8;11(6):266.
doi: 10.3390/pharmaceutics11060266.

Nanomaterial-Based Approaches for Neural Regeneration

Raluca Ioana Teleanu  1 , Oana Gherasim  2   3 , Tudor George Gherasim  4 , Valentina Grumezescu  5 , Alexandru Mihai Grumezescu  6 , Daniel Mihai Teleanu  7
Affiliations
Review

Nanomaterial-Based Approaches for Neural Regeneration

Raluca Ioana Teleanu et al. Pharmaceutics. .

Abstract

Mechanical, thermal, chemical, or ischemic injury of the central or peripheral nervous system results in neuron loss, neurite damage, and/or neuronal dysfunction, almost always accompanied by sensorimotor impairment which alters the patient's life quality. The regenerative strategies for the injured nervous system are currently limited and mainly allow partial functional recovery, so it is necessary to develop new and effective approaches for nervous tissue regenerative therapy. Nanomaterials based on inorganic or organic and composite or hybrid compounds with tunable physicochemical properties and functionality proved beneficial for the transport and delivery/release of various neuroregenerative-relevant biomolecules or cells. Within the following paragraphs, we will emphasize that nanomaterial-based strategies (including nanosized and nanostructured biomaterials) represent a promising alternative towards repairing and regenerating the injured nervous system.

Keywords: nanomaterial; nervous system injury; neuroregeneration.

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Conflict of interest statement

The authors declare no conflict of interest.

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