Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Sep;7(9):3353-7.
doi: 10.1128/mcb.7.9.3353-3357.1987.

Unique DNA repair properties of a xeroderma pigmentosum revertant

J E Cleaver  1 , F Cortés, L H Lutze, W F Morgan, A N Player, D L Mitchell
Affiliations

Unique DNA repair properties of a xeroderma pigmentosum revertant

J E Cleaver et al. Mol Cell Biol. 1987 Sep.

Abstract

A group A xeroderma pigmentosum revertant with normal sensitivity was created by chemical mutagenesis. It repaired (6-4) photoproducts normally but not pyrimidine dimers and had near normal levels of repair replication, sister chromatid exchange, and mutagenesis from UV light. The rate of UV-induced mutation in a shuttle vector, however, was as high as the rate in the parental xeroderma pigmentosum cell line.

PubMed Disclaimer

References

    1. Cancer Res. 1974 Dec;34(12):3318-25 - PubMed
    1. Mutat Res. 1987 Jan;183(1):69-74 - PubMed
    1. Biochim Biophys Acta. 1976 Aug 18;442(2):147-53 - PubMed
    1. Cell. 1977 May;11(1):223-32 - PubMed
    1. J Mol Biol. 1977 Jul 15;113(4):635-49 - PubMed

Publication types

Substances