Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Mar 22;11(3):e4298.
doi: 10.7759/cureus.4298.

Heavily Calcified Esthesioneuroblastoma in a 72-year-old

Affiliations
Case Reports

Heavily Calcified Esthesioneuroblastoma in a 72-year-old

Robert Maurer et al. Cureus. .

Abstract

A 72-year-old female presented with the complaint of declining vision. Workup included magnetic resonance imaging (MRI) which revealed a large enhancing mass extending into the nasal cavity, nasopharynx, and anterior cranial fossa. Computed tomography (CT) imaging revealed extensive calcification. Subsequent endonasal biopsy revealed the tumor to be an unusually calcified esthesioneuroblastoma (ENB). The patient elected for palliative measures. The case provides a basis for a discussion on rare esthesioneuroblastomas and highlights the possibility of extensive calcification on such tumors.

Keywords: esthesioneuroblastoma; olfactory neuroblastoma.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. T1 weighted axial MRI
Figure 2
Figure 2. T1 weighted post-contrast axial MRI
Figure 3
Figure 3. T1 weighted post-contrast coronal MRI
Figure 4
Figure 4. Axial non-contrast CT
Figure 5
Figure 5. Sagittal non-contrast CT
Figure 6
Figure 6. H&E staining of tumor at 200x magnification
Figure 7
Figure 7. Synaptophysin stain of tumor at 100x magnification

References

    1. Esthesioneuroblastoma: a general review of the cases published since the discovery of the tumour in 1924. Broich G, Pagliari A, Ottaviani F. https://www.researchgate.net/profile/Guido_Broich/publication/13966851_E.... Anticancer Res. 1997;17:2683–2706. - PubMed
    1. Ow TJ, Bell D, Kupferman ME, DeMonte F, Hanna EY. Neurosurg Clin N Am. Vol. 24. Neurosurgery Clinics; 2013. Esthesioneuroblastoma; pp. 51–65. - PubMed
    1. Esthesioneuroblastoma: a population-based analysis of survival and prognostic factors. Jethanamest D, Morris LG, Sikora AG, Kutler DI. Arch Otolaryngol Head Neck Surg. 2007;133:276–280. - PubMed
    1. Esthesioneuroblastoma: a meta-analysis and review. Dulguerov P, Allal AS, Calcaterra TC. Lancet Oncol. 2001;2:683–690. - PubMed
    1. Expression of the humanAchaete-scute 1 gene in olfactory neuroblastoma (esthesioneuroblastoma) Carney ME, O'Reilly RC, Sholevar B, et al. https://link.springer.com/article/10.1007/BF01054767. J Neurooncol. 1995;26:35–43. - PubMed

Publication types

LinkOut - more resources