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Comparative Study
. 1986;34(4):289-97.

Chemotherapy of human non-Hodgkin lymphoma (NHL) xenografts

L Kopper  1 , P Nagy, E Magyarosy, J Major
Affiliations
  • PMID: 3118646
Comparative Study

Chemotherapy of human non-Hodgkin lymphoma (NHL) xenografts

L Kopper et al. Acta Morphol Hung. 1986.

Abstract

Three human NHL (B-cell type) were established successfully as serially transplantable xenografts in artificially immunesuppressed CBA mice. All of them preserved the phenotypic characteristics of the original tumour even after several passages. The transplanted tumours were highly sensitive to cyclophosphamide and methotrexate, reflecting the results obtained in clinical practice, and relatively sensitive to dianhydrogalactitol.

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