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Review
. 2012 Nov 9;1(5):147-150.
doi: 10.1002/cld.92. eCollection 2012 Nov.

Primary prophylaxis of esophageal variceal bleeding

Douglas A Simonetto  1 , Vijay H Shah  1
Affiliations
Review

Primary prophylaxis of esophageal variceal bleeding

Douglas A Simonetto et al. Clin Liver Dis (Hoboken). .
No abstract available

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Figures

Figure 1
Figure 1
Schematic representation of the pathophysiology of portal hypertension in cirrhosis and the formation of esophageal varices.
Figure 2
Figure 2
Endoscopic appearances of esophageal varices. (A) Upper gastrointestinal endoscopy demonstrates small varices in the lower esophagus (arrows). (B) Upper gastrointestinal endoscopy demonstrates large esophageal varices with a fibrin plug (arrow), representing the site of recent bleeding.
Figure 3
Figure 3
Comparison of nonselective beta‐blockers versus placebo in the prevention of first variceal bleeding and mortality according to a meta‐analysis of 11 randomized controlled trials.6 *P < 0.05
Figure 4
Figure 4
Comparison of nonselective beta‐blockers versus VBL in the prevention of first variceal bleeding and mortality according to a meta‐analysis of 19 randomized controlled trials.23 *P < 0.05
Figure 5
Figure 5
Schematic diagram of American Association for the Study of Liver Diseases recommendations for primary prophylaxis of esophageal variceal bleeding. High risk for variceal bleeding includes Child‐Turcotte‐Pugh class B and C or the presence of red wales on varices. Abbreviation: EGD, esophagogastroduodenoscopy.
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