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Review
. 2019 Jun;37 Suppl 1(Suppl 1):62-65.
doi: 10.1002/hon.2586.

Multiple myeloma: Every year a new standard?

Affiliations
Review

Multiple myeloma: Every year a new standard?

S Vincent Rajkumar. Hematol Oncol. 2019 Jun.

Abstract

The treatment of myeloma is rapidly evolving. This article reviews the current diagnostic criteria, risk stratification, and approach to treatment of multiple myeloma. Treatment approach for both newly diagnosed and relapsed disease are discussed.

Keywords: myeloma; prognosis; therapy.

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Conflict of interest statement

Conflict of interest: No conflicts of interest to be disclosed.

Disclosure of Conflicts of Interest

SVR declares no conflict of interest.

References

    1. Rajkumar SV, Dimopoulos MA, Palumbo A, et al. International Myeloma Working Group Updated Criteria for the Diagnosis of MM. Lancet Oncol 2014;15:e538–48. - PubMed
    1. Kumar SK, Dispenzieri A, Lacy MQ, et al. Continued improvement in survival in MM: changes in early mortality and outcomes in older patients. Leukemia 2014;28:1122–8. - PMC - PubMed
    1. Kumar S, Paiva B, Anderson KC, et al. International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in MM. The Lancet Oncology 2016;17:e328–46. - PubMed
    1. Durie BGM, Hoering A, Abidi MH, et al. Bortezomib, Lenalidomide and Dexamethasone vs. Lenalidomide and Dexamethasone Induction Followed by Lenalidomide and Dexamethasone Maintenance in Patients with Newly Diagnosed Myeloma without Intent for Immediate Autologous Stem Cell Transplant: Results of the Randomised Phase III SWOG Trial S0777. Lancet 2017;389:519–27. - PMC - PubMed
    1. Rajkumar SV, Jacobus S, Callander NS, et al. Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed MM: an open-label randomised controlled trial. Lancet Oncol 2010;11:29–37. - PMC - PubMed