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Review
. 2019 Jul;123(1):18-22.
doi: 10.1038/s41437-019-0216-0. Epub 2019 Jun 12.

The journey of a molecular detective

David Sherratt  1
Affiliations
Review

The journey of a molecular detective

David Sherratt. Heredity (Edinb). 2019 Jul.
No abstract available

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Conflict of interest statement

The author declares that he has no conflict of interest.

Figures

Fig. 1
Fig. 1
Copy of a hand-written and hand-drawn page from Martin Boocock’s ‘Topological Tables’ (~1982). These set out to describe the topologies and outcomes of recombination events on recombination sites in different configurations. These Tables provided the basis for understand the resolvase recombination mechanism and the concept of a ‘topological filter’
See this image and copyright information in PMC

References

    1. Arthur A, Sherratt D. Dissection of the transposition process: a transposon-encoded site-specific recombination system. Mol Gen Genet. 1979;175:267–274. doi: 10.1007/BF00397226. - DOI - PubMed
    1. Aussel L, Barre FX, Aroyo M, Stasiak A, Stasiak AZ, Sherratt D. FtsK Is a DNA motor protein that activates chromosome dimer resolution by switching the catalytic state of the XerC and XerD recombinases. Cell. 2002;108:195–205. doi: 10.1016/S0092-8674(02)00624-4. - DOI - PubMed
    1. Badrinarayanan A, Reyes-Lamothe R, Uphoff S, Leake MC, Sherratt DJ. In vivo architecture and action of bacterial structural maintenance of chromosome proteins. Science. 2012;338:528–531. doi: 10.1126/science.1227126. - DOI - PMC - PubMed
    1. Blakely G, Colloms S, May G, Burke M, Sherratt D. Escherichia coli XerC recombinase is required for chromosomal segregation at cell division. New Biol. 1991;3:789–798. - PubMed
    1. Colloms SD, Bath J, Sherratt DJ. Topological selectivity in Xer site-specific recombination. Cell. 1997;88:855–864. doi: 10.1016/S0092-8674(00)81931-5. - DOI - PubMed

Substances

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