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. 1987;236(6):369-71.
doi: 10.1007/BF00377427.

Body fluids after CO2 inhalation: insight into panic mechanisms?

E Griez  1 , M A van den Hout, F Verstappen
Affiliations

Body fluids after CO2 inhalation: insight into panic mechanisms?

E Griez et al. Eur Arch Psychiatry Neurol Sci. 1987.

Abstract

Blood gases and electrolyte fluctuations were studied in arterial blood, after a single 35% CO2-65% O2 inhalation, which is known to trigger panic attacks in patients with panic disorder. The immediate effect of this maneuver was a brief hypercapnic acidosis followed by a slight alkalotic rebound, with shifts in Ca2+ and K+. The possible effect of these changes on neuronal membrane excitability is discussed, referring to recent experimental findings in panic provocation.

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