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Case Reports
. 2019 Jun 3;5(6):501-503.
doi: 10.1016/j.jdcr.2019.03.017. eCollection 2019 Jun.

Topiramate-induced reactive granulomatous dermatitis

Sara Mater  1 , Jonathan J Lee  2 , Jaroslaw Jedrych  2 , Misha Rosenbach  3 , Joseph C English 3rd  2
Affiliations
Case Reports

Topiramate-induced reactive granulomatous dermatitis

Sara Mater et al. JAAD Case Rep. .
No abstract available

Keywords: GA, granuloma annulare; RGD, reactive granulomatous dermatitis; diRGD, drug-induced reactive granulomatous dermatitis; drug-induced reactive granulomatous dermatitis; granuloma annulare; granulomatous dermatitis; reactive granulomatous dermatitis; topiramate.

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Figures

Fig 1
Fig 1
Clinical findings at presentation. Pink papules coalescing into linear serpiginous cords and expansile annular plaques with central clearing.
Fig 2
Fig 2
Histologic findings (low power). Scanning magnification shows a palisaded and interstitial lymphohistiocytic infiltrate in the dermis. (Original magnification: ×5.)
Fig 3
Fig 3
Histologic findings (high power). Higher power highlights a palisade of histiocytes and multinucleated giant cells surrounding a focus of necrobiosis. (Original magnification: ×40.)
Fig 4
Fig 4
Clinical findings after discontinuation of topiramate. Four months after discontinuation of topiramate, the patient experienced near-complete resolution of dermatologic findings.
See this image and copyright information in PMC

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References

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