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Case Reports
. 2019 Jun 4:28:100872.
doi: 10.1016/j.rmcr.2019.100872. eCollection 2019.

A series of two cases of rare tumors: Solitary fibrous tumor of the pleura

Hazim Bukamur  1 , Emhemmid Karem  2 , Serag Fares  3 , Saroj Sigdel  4 , Emad Alkhankan  1 , Fuad Zeid  1
Affiliations
Case Reports

A series of two cases of rare tumors: Solitary fibrous tumor of the pleura

Hazim Bukamur et al. Respir Med Case Rep. .

Abstract

Solitary fibrous tumors of the pleura (SFTPs) are rare neoplasms of mesenchymal origin most commonly arising in the pleura and have a benign biological behavior in the majority of cases. Most patients with SFTPs are asymptomatic; however, symptoms are mostly related to the mass effect within the thoracic cavity. Chest computed tomography (CT) scanning is the radiographic test of choice, but findings lack specificity. Surgical resection is the treatment of choice for most patients. Long-term survival after resection of benign SFTPs is excellent. In this case series, we present two females, one presented with shortness of breath (SOB) and nonproductive cough and the other one was referred because of abnormal x-ray findings. The histological as well as the immunohistochemical examination revealed the mass to be a solitary fibrous tumor of the pleura.

Keywords: Fibroblastic mesenchymal neoplasm; Pleural tumor; Solitary fibrous tumor.

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Figures

Fig. 1
Fig. 1
A CT scan of chest without contrast showed smooth well-defined mass measures 3.5 × 4.4 × 2.8 cm in size at the anterior portion of the left first rib.
Fig. 2
Fig. 2
A coronal plane of the CT scan of chest showing a smooth well-defined mass at the anterior apical portion of the left lung.
Fig. 3
Fig. 3
A sagittal plane of the CT scan of chest showing a smooth well-defined mass at the anterior apical portion of the left lung.
Fig. 4
Fig. 4
A positron emission tomography (PET) scan showed a 1.8 cm nodule at left upper lobe that is non-fluorodeoxyglucose (FDG) avid.
Fig. 5
Fig. 5
Low power view shows uniform cellular tumor with intralesional blood vessels.
Fig. 6
Fig. 6
Higher power shows epithelioid cells and numerous angulated blood vessels.
Fig. 7
Fig. 7
Tumor cells are positive immunohistochemical stain CD34.
Fig. 8
Fig. 8
Tumor cells are negative for immunohistochemical stain cytokeratin AE1/AE3.
Fig. 9
Fig. 9
A CT scan of the chest showing a 2 cm low attenuation mass at the superior aspect of left major fissure.
Fig. 10
Fig. 10
A positron emission tomography (PET) scan showed a 1.9 cm nodule adjacent to the left major fissure that is non-fluorodeoxyglucose (FDG) avid.
Fig. 11
Fig. 11
Low power view shows cellular spindle cell neoplasm.
Fig. 12
Fig. 12
Higher power shows monomorphic spindle cells.
Fig. 13
Fig. 13
Tumor cells are positive immunohistochemical stain CD34.
Fig. 14
Fig. 14
Tumor cells are negative for immunohistochemical stain cytokeratin AE1/AE3.
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