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Comment
. 2019 Jun 13;15(6):e1008154.
doi: 10.1371/journal.pgen.1008154. eCollection 2019 Jun.

Diffusion and function of Wnt ligands

Richard A Stewart  1 , Aravinda-Bharathi Ramakrishnan  1 , Ken M Cadigan  1
Affiliations
Comment

Diffusion and function of Wnt ligands

Richard A Stewart et al. PLoS Genet. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Several constructs used to study Wnt diffusion.
Endogenous Wg, Egl-20, and murine Wnt3 are depicted on the left, with their N-terminal signal sequences. NRT-Wg, Egl-20-YPet, and HA-tagged Wnt3 are shown on the right. NRT is a type II TM protein, so the C-terminal portion containing Wg will be extracellular. aa, amino acid; Egl-20, egg-laying defective-20; HA, hemagglutinin; NRT, neurotactin TM domain; TM, transmembrane; Wg, wingless; YPet, a yellow fluorescent protein derived from green fluorescent protein [29].
See this image and copyright information in PMC

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