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Review
. 2019 Jun 5;11(6):1273.
doi: 10.3390/nu11061273.

Dysbiosis and Prematurity: Is There a Role for Probiotics?

Maria Elisabetta Baldassarre  1 , Antonio Di Mauro  2 , Manuela Capozza  3 , Valentina Rizzo  4 , Federico Schettini  5 , Raffaella Panza  6 , Nicola Laforgia  7
Affiliations
Review

Dysbiosis and Prematurity: Is There a Role for Probiotics?

Maria Elisabetta Baldassarre et al. Nutrients. .

Abstract

Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant gut might have a role in feeding intolerance and pathogenesis of necrotizing enterocolitis. Despite several clinical trials and meta-analyses, it is still not clear if modulation of maternal and neonatal microbiota with probiotic supplementation decreases the risk of preterm birth and its complications.

Keywords: Premature” [MeSH]; “Dysbiosis” [MeSH]; “Infant; “Premature Birth” [MeSH]; “Probiotics” [MeSH].

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Conflict of interest statement

The authors declare no conflict of interest.

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