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. 1987 Dec;169(12):5841-4.
doi: 10.1128/jb.169.12.5841-5844.1987.

Regulation of the metR gene of Salmonella typhimurium

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Regulation of the metR gene of Salmonella typhimurium

M L Urbanowski et al. J Bacteriol. 1987 Dec.

Abstract

Regulation of the Salmonella typhimurium metR gene was studied by measuring beta-galactosidase levels in Escherichia coli strains lysogenic for a lambda bacteriophage carrying a metR-lacZ fusion. The results indicate that the metR gene is negatively regulated by its own gene product and that this autoregulation involves homocysteine as a corepressor. In addition, the results indicate that the metR gene is negatively regulated by the metJ gene product over a 70- to 80-fold range.

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