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Randomized Controlled Trial
. 2019 Dec;97(8):e1130-e1135.
doi: 10.1111/aos.14156. Epub 2019 Jun 13.

Impact of primary posterior capsulorhexis on regeneratory after-cataract and YAG laser rates with an acrylic micro-incision intraocular lens with plate haptics: 1-year and 3-year results

Rupert Menapace  1 , Sabine Schriefl  1 , Christoph Lwowski  1 , Christina Leydolt  1
Affiliations
Randomized Controlled Trial

Impact of primary posterior capsulorhexis on regeneratory after-cataract and YAG laser rates with an acrylic micro-incision intraocular lens with plate haptics: 1-year and 3-year results

Rupert Menapace et al. Acta Ophthalmol. 2019 Dec.

Abstract

Purpose: To evaluate the posterior capsule opacification (PCO) and YAG laser capsulotomy (YAG-LCT) rates with a plate-haptic acrylic micro-incision intraocular lens (IOL) and the impact of primary posterior capsulorhexis.

Methods: A total of 97 patients scheduled for immediate sequential bilateral cataract surgery underwent a randomized, prospective intraindividual comparison with the ZEISS Asphina 409MV plate-haptic acrylic IOL with the eyes receiving an additional primary posterior capsulorhexis (PPCR) or not. YAG-LCT and PCO rates were evaluated at 1 and 3 years. Three-year PCO rates were calculated with a 3-scenario method for eyes that underwent YAG-LCT between 1 and 3 years.

Results: A total of 56 patients were seen at 1 year, and 57 at 3 years. For the eyes without and with PPCR, YAG-LCT rates were 14.3% and 0% at 1 year, and 59.7% and 3.5% at 3 years, respectively. Opacification rates at 1 year were 0.55 ± 0.99 and 0.05 ± 0.21 for the central 2-mm optic zone. A total of 42 patients completed both the 1- and 3-year follow-up. Three-year opacification rates for the group without PPCR were 1.99 ± 2.20, 2.26 ± 2.66 and 3.66 ± 3.61 for the central 2-mm zone and 2.57 ± 2.07, 3.13 ± 3.03 and 4.09 ± 3.34 for the 4.5-mm zone for the best, extrapolated and worst-case scenarios, respectively.

Conclusion: The ZEISS Asphina 409MV plate-haptic acrylic IOL exhibited unusually high YAG-LCT and PCO rates with standard in-the-bag implantation. PPCR was safe and effective in preventing central opacification and the need for YAG laser treatment.

Keywords: YAG laser capsulotomy; ZEISS CT Asphina 409MV plate-haptic acrylic micro-incision intraocular lens; posterior capsule opacification; primary posterior capsulorhexis.

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Figures

Figure 1
Figure 1
Design of the ZEISS CT Asphina 409M IOL Model. On the left: AutoCAD analysis of posterior optic edge sharpness of a ×25 magnification scanning electron microscopy (SEM) photograph of a 20 dioptre IOL. The white line represents a 40‐μm radius circle. The area within the red lines corresponds to the deviation from the ideal square (Courtesy by Liliana Werner).
Figure 2
Figure 2
PCO rates at 1 and 3 years for different eccentricities.
Figure 3
Figure 3
Three eye pairs representing different severities of PCO formation in the standard eye and the efficacy of PPCR in preventing LEC ingrowth.
Figure 4
Figure 4
Four examples of eyes with peripheral to near‐central overgrowth.
See this image and copyright information in PMC

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References

    1. Buehl W, Heinzl H, Mittlboeck M & Findl O (2008): Statistical problems caused by missing data resulting from neodymium: YAG laser capsulotomies in long‐term posterior capsule opacification studies: problem identification and possible solutions. J Cataract Refract Surg 34: 268–273. - PubMed
    1. Faschinger CW & Eckhardt M (1999): Complete capsulorhexis opening occlusion despite capsular tension ring implantation. J Cataract Refract Surg 25: 1013–1015. - PubMed
    1. Findl O, Buehl W, Menapace R, Georgopoulos M, Rainer G, Siegl H, Kaider A & Pinz A (2003): Comparison of 4 methods for quantifying posterior capsule opacification. J Cataract Refract Surg 29: 106–111. - PubMed
    1. Georgopoulos M, Menapace R, Findl O, Rainer G, Petternel V & Kiss B (2001): Posterior continuous curvilinear capsulorhexis with hydrogel and silicone intraocular lens implantation: development of capsulorhexis size and capsule opacification. J Cataract Refract Surg 27: 825–832. - PubMed
    1. Leydolt C, Kriechbaum K, Schriefl S, Pachala M & Menapace R (2013): Posterior capsule opacification and neodymium:YAG rates with 2 single‐piece hydrophobic acrylic intraocular lenses: three‐year results. J Cataract Refract Surg 39: 1886–1892. - PubMed

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