Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 May;11(Suppl 2):S112-S125.
doi: 10.4103/JPBS.JPBS_34_19.

Monomer Modifications of Denture Base Acrylic Resin: A Systematic Review and Meta-analysis

R Ajay  1 , K Suma  2 , Seyed Asharaf Ali  2
Affiliations
Review

Monomer Modifications of Denture Base Acrylic Resin: A Systematic Review and Meta-analysis

R Ajay et al. J Pharm Bioallied Sci. 2019 May.

Abstract

Background: Methyl methacrylate monomer of denture base resins was modified with several monomers to achieve better physico-mechanical properties without compromising the biocompatibility. However, there are no consensuses on the best strategy to achieve best modified monomer.

Purpose: To identify and evaluate the differences in the properties between conventional and modified monomers and to verify the influence of several variables on the properties of denture base acrylic resin.

Materials and methods: This study was executed by following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. In-vitro studies that investigated the properties of conventional and modified monomers were selected. Searches were carried out in the Ebscohost, PubMed, Semantic scholar and J-stage databases. The search commenced from the year 1995 and the last search was done till November 2018. A comparison was performed between modified and unmodified monomers. The analyses were carried out using fixed-effect models.

Results: The meta-analysis results showed high heterogeneity in all aspects, and higher flexural strength for monomers modified with 20% methacrylic acid.

Conclusion: Although the articles included in this meta-analysis showed high heterogeneity and high risk of bias, the in-vitro literature seems to suggest that use of modified monomers could improve the properties of denture base resins. Other variants of monomer modifications and their tested parameters were discussed in this systematic review as well. Dimensional accuracy is an unexplored variable to be evaluated extensively in the future researches.

Keywords: Methyl-methacrylate; Monomer; biocompatibility; properties.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
PRISMA flow chart
Figure 2
Figure 2
Forest plot of comparison of 100% MMA and 80% MMA + 20% MAA
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. al-Mulla MA, Murphy WM, Huggett R, Brooks SC. Effect of water and artificial saliva on mechanical properties of some denture-base materials. Dent Mater. 1989;5:399–402. - PubMed
    1. Anderson GC, Schulte JK, Arnold TG. Dimensional stability of injection and conventional processing of denture base acrylic resin. J Prosthet Dent. 1988;60:394–8. - PubMed
    1. Anthony DH, Peyton FA. Evaluating dimensional accuracy of denture bases with a modified comparator. J Prosthet Dent. 1959;9:683–92.
    1. Anthony DH, Peyton FA. Dimensional accuracy of various denture-base materials. J Prosthet Dent. 1962;12:67–81.
    1. Rodriguez LS, Paleari AG, Giro G, de Oliveira Junior NM, Pero AC, Compagnoni MA. Chemical characterization and flexural strength of a denture base acrylic resin with monomer 2-tert-butylaminoethyl methacrylate. J Prosthodont. 2013;22:292–7. - PubMed