Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 May 31;2019(5):omz030.
doi: 10.1093/omcr/omz030. eCollection 2019 May.

Calcium crystal-associated arthropathy mimicking a febrile systemic inflammatory disease in an elderly patient

Affiliations
Case Reports

Calcium crystal-associated arthropathy mimicking a febrile systemic inflammatory disease in an elderly patient

Anna Paula Duque Sousa et al. Oxf Med Case Reports. .

Abstract

Crystal formation and deposition in the joints is an important and common cause of acute arthritis. The disease may present with fever and systemic signs. In this report, we describe the case of a 70-year-old man, who presented with a sudden and incapacitating polyarthritis of large and small joints, fever, asthenia and leukocytosis. After extensive investigation, radiography of the joints showed the presence of chondrocalcinosis. A few days after the beginning of the treatment with colchicine, he became completely asymptomatic, drawing one's attention of calcium crystal-associated arthropathy as a cause of febrile systemic inflammatory disease particularly in elderly population.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Radiographs showing chondrocalcinosis in meniscus of the knee, fibrocartilage of the wrist and elbow.
Figure 2
Figure 2
Radiograph of the right shoulder revealing joint space narrowing and irregularity of the glenohumeral bone surface compatible with ‘Milwaukee shoulder’.

Similar articles

Cited by

  • Autoinflammatory Mechanisms in Crystal-Induced Arthritis.
    Oliviero F, Bindoli S, Scanu A, Feist E, Doria A, Galozzi P, Sfriso P. Oliviero F, et al. Front Med (Lausanne). 2020 Apr 30;7:166. doi: 10.3389/fmed.2020.00166. eCollection 2020. Front Med (Lausanne). 2020. PMID: 32426360 Free PMC article. Review.

References

    1. Ea HK, Liote F. Diagnosis and clinical manifestations of calcium pyrophosphate and basic calcium phosphate crystal deposition diseases. Rheum Dis Clin North Am 2014;40:207–229. - PubMed
    1. Ferrone C, Andracco R, Cimmino MA. Calcium pyrophosphate deposition disease: clinical manifestations. Reumatismo 2012;63:246–252. - PubMed
    1. Agudelo CA, Wise CM. Crystal-associated arthritis. Clin Geriatr Med 1998;14:495–513. - PubMed
    1. Doherty M, Dieppe P, Watt I. Pyrophosphate arthropathy: a prospective study. Br J Rheumatol 1993;32:189–196. - PubMed
    1. Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006;440:237–241. - PubMed

Publication types