Naloxegol for opioid-induced sphincter of Oddi spasm/dysfunction
- PMID: 31201151
- DOI: 10.1136/bmjspcare-2019-001808
Naloxegol for opioid-induced sphincter of Oddi spasm/dysfunction
Abstract
The paper describes a case report of a patient with a significant history of opioid-induced dysfunction of the sphincter of Oddi, who required morphine sulfate to manage oral mucositis pain, and who was successfully treated with concomitant oral naloxegol (Moventig: Kyowa Kirin, Galashiels, UK).
Keywords: analgesics, opioid; naloxegol; narcotic antagonists; sphincter of Oddi.
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Conflict of interest statement
Competing interests: AND has received honoraria for lecturing and for attending advisory boards, and research funding from Kyowa Kirin. CL has received an honorarium for lecturing from Kyowa Kirin.
Similar articles
-
▼Naloxegol for opioid-induced constipation.Drug Ther Bull. 2015 Dec;53(12):138-40. doi: 10.1136/dtb.2015.12.0369. Drug Ther Bull. 2015. PMID: 26660436 Review.
-
The impact of naloxegol on anal sphincter function - Using a human experimental model of opioid-induced bowel dysfunction.Eur J Pharm Sci. 2018 May 30;117:187-192. doi: 10.1016/j.ejps.2018.02.008. Epub 2018 Feb 9. Eur J Pharm Sci. 2018. PMID: 29432808 Clinical Trial.
-
Naloxegol to Treat Constipation in a Patient Taking Opioids for Cancer Pain: A Case Report.A A Pract. 2018 Jul 1;11(1):22-24. doi: 10.1213/XAA.0000000000000726. A A Pract. 2018. PMID: 29634552
-
Relief by naloxone of morphine-induced spasm of the sphincter of Oddi in a post-cholecystectomy patient.J Emerg Med. 2001 Aug;21(2):129-31. doi: 10.1016/s0736-4679(01)00355-9. J Emerg Med. 2001. PMID: 11489400
-
Evaluating naloxegol for the treatment of opioid-induced constipation.Expert Opin Pharmacother. 2020 Jun;21(8):883-891. doi: 10.1080/14656566.2020.1735354. Epub 2020 Mar 4. Expert Opin Pharmacother. 2020. PMID: 32129103 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources