APPealing for a role in cellular iron efflux
- PMID: 31201240
- PMCID: PMC6579459
- DOI: 10.1074/jbc.L119.009216
APPealing for a role in cellular iron efflux
Conflict of interest statement
The authors declare that they have no conflicts of interest with the contents of this article
Comment in
-
Reply to Lahiri et al.: APPealing for a role in cellular iron efflux.J Biol Chem. 2019 Jun 14;294(24):9366. doi: 10.1074/jbc.RL119.009249. J Biol Chem. 2019. PMID: 31201241 Free PMC article. No abstract available.
Comment on
-
Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux.J Biol Chem. 2019 Mar 15;294(11):4202-4214. doi: 10.1074/jbc.RA118.005142. Epub 2019 Jan 15. J Biol Chem. 2019. PMID: 30647129 Free PMC article.
Similar articles
-
Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux.J Biol Chem. 2019 Mar 15;294(11):4202-4214. doi: 10.1074/jbc.RA118.005142. Epub 2019 Jan 15. J Biol Chem. 2019. PMID: 30647129 Free PMC article.
-
The Ferroxidase Hephaestin But Not Amyloid Precursor Protein is Required for Ferroportin-Supported Iron Efflux in Primary Hippocampal Neurons.Cell Mol Neurobiol. 2018 May;38(4):941-954. doi: 10.1007/s10571-017-0568-z. Epub 2017 Nov 25. Cell Mol Neurobiol. 2018. PMID: 29177638 Free PMC article.
-
β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin.PLoS One. 2014 Dec 2;9(12):e114174. doi: 10.1371/journal.pone.0114174. eCollection 2014. PLoS One. 2014. PMID: 25464026 Free PMC article.
-
Cellular iron: ferroportin is the only way out.Cell Metab. 2005 Mar;1(3):155-7. doi: 10.1016/j.cmet.2005.02.005. Cell Metab. 2005. PMID: 16054057 Review.
-
Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity.Int J Mol Sci. 2019 Feb 25;20(4):994. doi: 10.3390/ijms20040994. Int J Mol Sci. 2019. PMID: 30823541 Free PMC article. Review.
Cited by
-
Overdosing on iron: Elevated iron and degenerative brain disorders.Exp Biol Med (Maywood). 2020 Oct;245(16):1444-1473. doi: 10.1177/1535370220953065. Epub 2020 Sep 2. Exp Biol Med (Maywood). 2020. PMID: 32878460 Free PMC article. Review.
-
Iron-responsive-like elements and neurodegenerative ferroptosis.Learn Mem. 2020 Aug 17;27(9):395-413. doi: 10.1101/lm.052282.120. Print 2020 Sep. Learn Mem. 2020. PMID: 32817306 Free PMC article. Review.
-
Reply to Lahiri et al.: APPealing for a role in cellular iron efflux.J Biol Chem. 2019 Jun 14;294(24):9366. doi: 10.1074/jbc.RL119.009249. J Biol Chem. 2019. PMID: 31201241 Free PMC article. No abstract available.
References
-
- Dlouhy A. C., Bailey D. K., Steimle B. L., Parker H. V., and Kosman D. J. (2019) Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux. J. Biol. Chem. 294, 4202–4214 10.1074/jbc.RA118.005142 - DOI - PMC - PubMed
-
- Bandyopadhyay S., Cahill C., Balleidier A., Huang C., Lahiri D. K., Huang X., and Rogers J. T. (2013) Novel 5′ untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for Down syndrome and Alzheimer's disease. PLoS One 8, e65978 10.1371/journal.pone.0065978 - DOI - PMC - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical