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. 2019 Mar;485(1):101-103.
doi: 10.1134/S1607672919020017. Epub 2019 Jun 14.

Optimization of Heterologous Expression of Insulin Receptor-Related Receptor Ectodomain

A A Mozhaev  1   2 , A N Orsa  3 , I E Deyev  3 , V I Shvets  4 , A G Petrenko  3
Affiliations

Optimization of Heterologous Expression of Insulin Receptor-Related Receptor Ectodomain

A A Mozhaev et al. Dokl Biochem Biophys. 2019 Mar.

Abstract

In this paper, we present an approach to optimize the heterologous expression of the receptor tyrosine kinase IRR, which further simplifies the purification of the IRR from the medium and increases the final yield. The approach proposed by us can find application in the biotechnological production of other large-scale recombinant proteins produced for medical purposes.

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References

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