Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1987;412(1):23-6.
doi: 10.1007/BF00750726.

Immunohistochemical distribution of vitamin B12 R-binder in renal cell carcinoma

K Ogawa  1 , H Kudo, Y C Kim, Y Nakashima, G Ohshio, H Yamabe, M Inada, Y Hamashima
Affiliations
Comparative Study

Immunohistochemical distribution of vitamin B12 R-binder in renal cell carcinoma

K Ogawa et al. Virchows Arch A Pathol Anat Histopathol. 1987.

Abstract

Renal cell carcinomas and normal kidney tissues were examined for the expression of vitamin B12 R-binder by the indirect immunoperoxidase method. In normal kidney tissue, the presence of the vitamin B12 R-binder was shown to be confined to the straight portion (pars recta) of proximal tubules. Seven of the 38 cases of renal cell carcinoma (18%) expressed the vitamin B12 R-binder antigen. This provides a further evidence of the proximal tubular nature of renal cell carcinoma, and suggests that a small proportion of renal cell carcinomas originate from the straight portion of the renal proximal tubules.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Gut. 1987 Mar;28(3):339-45 - PubMed
    1. Cancer. 1970 Oct;26(4):780-7 - PubMed
    1. Nature. 1960 Apr 30;186:402-3 - PubMed
    1. J Immunol. 1967 Dec;99(6):1199-210 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 May;82(9):2955-9 - PubMed

Publication types

Substances

LinkOut - more resources