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Comparative Study
. 1987;412(1):23-6.
doi: 10.1007/BF00750726.

Immunohistochemical distribution of vitamin B12 R-binder in renal cell carcinoma

K Ogawa  1 , H Kudo, Y C Kim, Y Nakashima, G Ohshio, H Yamabe, M Inada, Y Hamashima
Affiliations
Comparative Study

Immunohistochemical distribution of vitamin B12 R-binder in renal cell carcinoma

K Ogawa et al. Virchows Arch A Pathol Anat Histopathol. 1987.

Abstract

Renal cell carcinomas and normal kidney tissues were examined for the expression of vitamin B12 R-binder by the indirect immunoperoxidase method. In normal kidney tissue, the presence of the vitamin B12 R-binder was shown to be confined to the straight portion (pars recta) of proximal tubules. Seven of the 38 cases of renal cell carcinoma (18%) expressed the vitamin B12 R-binder antigen. This provides a further evidence of the proximal tubular nature of renal cell carcinoma, and suggests that a small proportion of renal cell carcinomas originate from the straight portion of the renal proximal tubules.

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References

    1. Gut. 1987 Mar;28(3):339-45 - PubMed
    1. Cancer. 1970 Oct;26(4):780-7 - PubMed
    1. Nature. 1960 Apr 30;186:402-3 - PubMed
    1. J Immunol. 1967 Dec;99(6):1199-210 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 May;82(9):2955-9 - PubMed

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