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Comment
. 2019 Oct 15;200(8):1069-1070.
doi: 10.1164/rccm.201905-0962LE.

Understanding Hyperlactatemia in Sepsis: Are We There Yet?

Marek Nalos  1   2 , Robert Robergs  3
Affiliations
Comment

Understanding Hyperlactatemia in Sepsis: Are We There Yet?

Marek Nalos et al. Am J Respir Crit Care Med. .
No abstract available

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Comment in

Comment on

  • Understanding Lactatemia in Human Sepsis. Potential Impact for Early Management.
    Gattinoni L, Vasques F, Camporota L, Meessen J, Romitti F, Pasticci I, Duscio E, Vassalli F, Forni LG, Payen D, Cressoni M, Zanella A, Latini R, Quintel M, Marini JJ. Gattinoni L, et al. Am J Respir Crit Care Med. 2019 Sep 1;200(5):582-589. doi: 10.1164/rccm.201812-2342OC. Am J Respir Crit Care Med. 2019. PMID: 30985210 Clinical Trial.

References

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    1. Gattinoni L, Vasques F, Camporota L, Meessen J, Romitti F, Pasticci I, et al. Understanding lactatemia in human sepsis: potential impact for early management. Am J Respir Crit Care Med. 2019;200:582–589. - PubMed
    1. Robergs RA. Competitive cation binding computations of proton balance for reactions of the phosphagen and glycolytic energy systems within skeletal muscle. PLoS One. 2017;12:e0189822. - PMC - PubMed
    1. Hernández G, Ospina-Tascón GA, Damiani LP, Estenssoro E, Dubin A, Hurtado J, et al. The ANDROMEDA SHOCK Investigators and the Latin America Intensive Care Network (LIVEN) Effect of a resuscitation strategy targeting peripheral perfusion status vs serum lactate levels on 28-day mortality among patients with septic shock: the ANDROMEDA-SHOCK randomized clinical trial. JAMA. 2019;321:654–664. - PMC - PubMed
    1. Levy B, Desebbe O, Montemont C, Gibot S. Increased aerobic glycolysis through beta2 stimulation is a common mechanism involved in lactate formation during shock states. Shock. 2008;30:417–421. - PubMed