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. 2019 Oct;25(7):1822-1828.
doi: 10.1111/odi.13147. Epub 2019 Jul 2.

Distant metastases in newly diagnosed tongue squamous cell carcinoma

Xinjia Cai  1 , Junhui Huang  1
Affiliations

Distant metastases in newly diagnosed tongue squamous cell carcinoma

Xinjia Cai et al. Oral Dis. 2019 Oct.

Abstract

Objective: To characterize the incidence and survivals of patients with distant metastases in newly diagnosed tongue squamous cell carcinoma.

Materials and methods: Patients with distant metastases in newly diagnosed tongue squamous cell carcinoma were collected from the Surveillance, Epidemiology, and End Results database. Data were classified by sex, age, race, insurance status, T stage, N stage and grade. Multivariable logistic and Cox regression were used to demonstrate risk factors of the presence of distant metastases and hazards related to mortality, respectively.

Results: We found 92 patients with distant metastases in newly diagnosed tongue squamous cell carcinoma, including lung, bone, liver, and brain, representing 1.08% of the entire cohort. 69 were male and 23 were female. Median survival among patients with distant metastases was 4.0 months.

Conclusion: The study describes the incidence and prognosis of patients with distant metastases in newly diagnosed tongue squamous cell carcinoma based on population estimates. The findings lend support to closely monitor the development of distant metastases among patients with predictors at the time of diagnosis of tongue squamous cell carcinoma.

Keywords: distant metastases; incidence; survival; tongue squamous cell carcinoma.

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References

REFERENCES

    1. Aires, F. T., Lin, C. S., Matos, L. L., Kulcsar, M. A. V., & Cernea, C. R. (2017). Risk factors for distant metastasis in patients with oral cavity squamous cell carcinoma undergoing surgical treatment. ORL Journal of Oto-Rhino-Laryngology and Its Related Specialties, 79(6), 347-355. https://doi.org/10.1159/000485627
    1. Amit, M., Yen, T.-C., Liao, C.-T., Chaturvedi, P., Agarwal, J. P., Kowalski, L. P., … Gil, Z. (2013). Improvement in survival of patients with oral cavity squamous cell carcinoma: An international collaborative study. Cancer, 119(24), 4242-4248. https://doi.org/10.1002/cncr.28357
    1. de Mones, E., Bertolus, C., Salaun, P. Y., Dubrulle, F., Ferrie, J. C., & Temam, S. … Moriniere, S. (2013). Initial staging of squamous cell carcinoma of the oral cavity, larynx and pharynx (excluding nasopharynx). Part 2: Remote extension assessment and exploration for secondary synchronous locations outside of the upper aerodigestive tract. 2012 SFORL guidelines. European Annals of Otorhinolaryngology, Head and Neck Diseases, 130(2), 107-112. https://doi.org/10.1016/j.anorl.2012.09.003
    1. Garavello, W., Ciardo, A., Spreafico, R., & Gaini, R. M. (2006). Risk factors for distant metastases in head and neck squamous cell carcinoma. Archives of Otolaryngology-head & Neck Surgery, 132(7), 762-766. https://doi.org/10.1001/archotol.132.7.762
    1. Hasegawa, T., Tanakura, M., Takeda, D., Sakakibara, A., Akashi, M., Minamikawa, T., & Komori, T. (2015). Risk factors associated with distant metastasis in patients with oral squamous cell carcinoma. Otolaryngology - Head and Neck Surgery, 152(6), 1053-1060. https://doi.org/10.1177/0194599815580980

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